!!

Welcome Guest

You are viewing this forum as a guest therefore You are Not Allowed to Post and Reply and You are not allowed to view links. Register or Login

collapse

* Search


* Recent Replies

How Can I Change Or Beautify My New YouTube Page by [Not Shown, Login to View]
[Yesterday at 03:29 PM]


Effective Paid Traffic Channel by [Not Shown, Login to View]
[Yesterday at 01:55 PM]


WordPress font by [Not Shown, Login to View]
[Yesterday at 12:42 PM]


How long by [Not Shown, Login to View]
[Oct 18, 2017]


pdf (ebook) from laptop to gmail acoun by [Not Shown, Login to View]
[Oct 18, 2017]


facebook ads by [Not Shown, Login to View]
[Oct 18, 2017]


Website Traffic Season 12 - Amazing all-in-one tool for Google, Youtube, Amazon. by [Not Shown, Login to View]
[Oct 15, 2017]


Show/Hide Widgets in Blogspot Mobile Template by [Not Shown, Login to View]
[Oct 15, 2017]


How to Get Original Image For My Local News Blog by [Not Shown, Login to View]
[Oct 15, 2017]


how to create ebook covers by [Not Shown, Login to View]
[Oct 15, 2017]


Cheapest domain site and purchase with master card by [Not Shown, Login to View]
[Oct 05, 2017]


Amazon Identity Verification by [Not Shown, Login to View]
[Sep 28, 2017]


Any monthly charges from Paypal? by [Not Shown, Login to View]
[Sep 22, 2017]


Using RSS Gadget by [Not Shown, Login to View]
[Sep 22, 2017]


Old WordPress inbuilt themes by [Not Shown, Login to View]
[Sep 22, 2017]


how can i put html text and html tag into the notepad by [Not Shown, Login to View]
[Sep 18, 2017]


change from .blogspot.com to .com by [Not Shown, Login to View]
[Sep 17, 2017]


HTML code for Menu Buttons by [Not Shown, Login to View]
[Sep 17, 2017]


Buying Facebook group for traffic by [Not Shown, Login to View]
[Sep 16, 2017]


MBE 104_7_Building a Forum. by [Not Shown, Login to View]
[Sep 16, 2017]


Web Design Review by [Not Shown, Login to View]
[Sep 14, 2017]


Blogspot Label or page? by [Not Shown, Login to View]
[Sep 13, 2017]


Adding HTML Code to Blogspot by [Not Shown, Login to View]
[Sep 13, 2017]


My traffic sources by [Not Shown, Login to View]
[Sep 13, 2017]


Google Keyword Tool Asking for card details by [Not Shown, Login to View]
[Sep 04, 2017]


Alternative way to buy a domain and host by [Not Shown, Login to View]
[Aug 28, 2017]


The number of times to post new content in a blog by [Not Shown, Login to View]
[Aug 27, 2017]


Problem on Adding widget to feedburner by [Not Shown, Login to View]
[Aug 27, 2017]


wer to get good website content by [Not Shown, Login to View]
[Aug 24, 2017]


Relevance of my blog name to making money by [Not Shown, Login to View]
[Aug 24, 2017]

Author Topic: 12 Things You Didn’t Know About the Ebola Virus Disease  (Read 1349 times)

0 Members and 1 Guest are viewing this topic.

Offline [Not Shown, Login to View]

  • Administrator
  • Level: Mentor
  • ******
  • Posts: 259676
  • Respect: +7996
  • Gender: Male
  • Location: Benin City
  • 18th Chamber
  • My Rank: 85
What is Ebola Virus?

Ebola virus disease (also known as Ebola hemorrhagic fever), along with being one of mankind’s deadliest diseases, is also one of its most brutal. It causes extreme body aches, high fever, profuse vomiting, diarrhea and heavy internal and external bleeding, sometimes through body orifices and the pores of the skin. It is caused by a virus known as Ebola virus which was first identified in 1976.

Symptoms can manifest themselves between two and 21 days after exposure and usually begin with headaches and fever. There is no cure for the disease, which has been fatal in up to 90 percent of patients during some outbreaks, though the current outbreak has killed about 60 percent of those so far infected.

According the the World Health Organization, treatments include managing the patient’s fluids and electrolytes, as well as blood pressure and kidney function, all of which are in jeopardy as the infected bleed out of organs and even blood vessels. Read more about Ebola here: You are not allowed to view links. Register or Login

Some countries in West Africa are battling a deadly Ebola outbreak which has killed at least 887 people, mostly in Liberia, Guinea and Sierra Leone (and a few in Nigeria) in more than 1900 cases since March 2014.

Some Key Facts About Ebola
Recently, the US Embassy put out a circular concerning Ebola which includes how to recognise it and how to prevent yourself from getting infected. Below are some of the key points of that circular:

  1  The suspected reservoirs for Ebola are fruit bats.
  2  Transmission to humans is thought to originate from infected bats or primates that have become infected by bats.
  3  Undercooked infected bat and primate (bush) meat transmits the virus to humans.
  4  Human to human transmission is only achieved by physical contact with a person who is acutely and gravely ill from the Ebola virus or their body fluids.
  5  Transmission among humans is almost exclusively among caregiver family members or health care workers tending to the very ill.
  6  The virus is easily killed by contact with soap, bleach, sunlight, or drying. A washing machine will kill the virus in clothing saturated with infected body fluids.
  7  A person can incubate the virus without symptoms for 2-21 days, the average being 5-8 days before becoming ill. THEY ARE NOT CONTAGIOUS until they are acutely ill.
  8  Only when ill does the viral load express itself first in the blood and then in other bodily fluids (to include vomit, feces, urine, breast milk, semen and sweat).
  9  If you are walking around you are not infectious to others.
  10  There are documented cases from Kikwit, DRC of an Ebola outbreak in a village that had the custom of children never touching an ill adult. Children living for days in small one room huts with parents who died from Ebola did not become infected.
  11  You cannot contract Ebola by handling money, buying local bread or swimming in a pool.
  12  As always practice good hand washing techniques, but you will not contract Ebola if you do not touch a dying person.

Please Share this with all your friends and family on Facebook and Twitter, it may save a life.


Leave it for God, don't worry yourself. Leave it for God, don't cry no more.

Offline [Not Shown, Login to View]

  • Forum Guide
  • Level 4 (Dedicated)
  • ******
  • Posts: 1056
  • Respect: +267
  • Gender: Male
  • Location: Ibadan, Oyo State of Nigeria
  • 1st Chamber
  • My Rank: 86
@ Boss Tony - Thanks for sharing the educative health cautions piece.  May we not experience outbreak of Ebola deadliest disease in our dear country Nigeria, IJN....
Knowledge Is Power – Seek For It

Offline [Not Shown, Login to View]

  • Level 3 (Regular)
  • ***
  • Posts: 114
  • Respect: +15
  • Gender: Male
  • Location: Lagos
  • 1st chamber
  • My Rank: 6
    • Focus-Tiens
@MacFally: It's already in Nigeria. You should imbibe the preventive measures he outlined here, teach your young ones/loved ones to do same.
FREE bulk SMS @ You are not allowed to view links. Register or Login

Offline [Not Shown, Login to View]

  • Forum Guide
  • Level 4 (Dedicated)
  • ******
  • Posts: 1056
  • Respect: +267
  • Gender: Male
  • Location: Ibadan, Oyo State of Nigeria
  • 1st Chamber
  • My Rank: 86
You are not allowed to view links. Register or Login
@MacFally: It's already in Nigeria. You should imbibe the preventive measures he outlined here, teach your young ones/loved ones to do same.

@ Alexis29 -  Yah, I agree that Ebola is already in Nigeria but it is not yet outbreaking; hence my prayer is still in order.....
Knowledge Is Power – Seek For It

Offline [Not Shown, Login to View]

  • Administrator
  • Level: Mentor
  • ******
  • Posts: 259676
  • Respect: +7996
  • Gender: Male
  • Location: Benin City
  • 18th Chamber
  • My Rank: 85
How to Protect Yourself from Getting the Virus

Here are some ways to Protect yourself from this deadly disease. Please share this information with your friends and family so that they will be informed:

    Ensure that meat is properly cooked before eating (if possible, avoid bush meat and interaction with animals such as bats, monkeys, pigs etc.)
    Avoid hand shake as much as possible.(wash your hands frequently with disinfectants)
    Avoid touching contaminated needles or surfaces.
    An Ebola victim in hospital
    Avoid unnecessary visiting of hospitals. (use facial masks and hand gloves when caring for any sick person)
    Avoid religious healing centers
    Alert and report to health professionals and the general public, when you notice someone with the symptoms of Ebola.
    Avoid attending burials (wear protective clothing or ”Ebola suits” such as masks, gloves, gowns, and goggles if you must touch a dead or sick body. Those who care for a sick person or bury someone who has died from the disease often get the virus)
    If you fall sick, avoid going to public places.(isolation of Ebola HF patients from contact with unprotected persons is important to prevent the spread.)

What to Do If You Suspect that You Or Someone you Know Has Ebola?

Call the Ebola Helpline on +23480032652437 IMMEDIATELY to speak with Health Officials if you’re in Nigeria. Airtime is free on this number.

Leave it for God, don't worry yourself. Leave it for God, don't cry no more.

Offline [Not Shown, Login to View]

  • Forum Guide
  • Level 4 (Dedicated)
  • ******
  • Posts: 1056
  • Respect: +267
  • Gender: Male
  • Location: Ibadan, Oyo State of Nigeria
  • 1st Chamber
  • My Rank: 86
Thank u very much Boss Tony - Prevention is better than cure....
Knowledge Is Power – Seek For It

Offline [Not Shown, Login to View]

  • Forum Guide
  • Level 3 (Regular)
  • ******
  • Posts: 399
  • Respect: +42
  • Gender: Male
  • Location: Port Harcourt, Nigeria
  • You Won't Shrink if you can think.
  • My Rank: 61
    • http://hotbusinesslink.com
The Boss, we are very grateful for this protective information. My prayer is that non of us will ever experience Ebola virus disease... IJN.
You are not allowed to view links. Register or Login

Offline [Not Shown, Login to View]

  • Level 3 (Regular)
  • ***
  • Posts: 325
  • Respect: +71
  • Gender: Female
  • Location: Abuja
  • My Soul Praise the Lord
  • My Rank: 113
Thank you boss for you care and concern, it's a nice information/reminder to us all.

If only people could fear God more than this Ebola and watch out more for the second coming of Jesus Christ or, fear hell fire more than the fear of contacting this sickness it would really have been a better world here on earth and more importantly there in eternity.

Well, let God keep us for this short period that we have left on this earth. Even if each of us has 100 yrs more to live lets always remember that it is too short to be compared with eternity. The best life to live is the life in Christ.

As for Ebola take the necessary precautions but no need to be afraid, it's not our portion.

We are children of light and there can not be found any darkness in us (for any one who is serving God in spirit and in truth). If you're still walking in darkness better COME TO JESUS NOW!!! We are in the last days of this evil time. These are the signs of the coming of christ, be alert oh!!! It is really really close. The next news on TV might be that some people have disappeared and are no where to be found (rapture). If you need help on how to be genuinely born again just give me a personal message. God bless.
Forward ever, the best is yet to come. You are not allowed to view links. Register or Login

Offline [Not Shown, Login to View]

  • Forum Guide
  • Level 4 (Dedicated)
  • ******
  • Posts: 1056
  • Respect: +267
  • Gender: Male
  • Location: Ibadan, Oyo State of Nigeria
  • 1st Chamber
  • My Rank: 86

Ebola Virus: Cured Patient Should Avoid carnal knowledge For Eight Weeks


 The Nigerian Institute of Medical Research (NIMR) has warned that infected men who have recovered from the killer Ebola virus disease (EVD) can still transmit the virus through their semen for up to seven weeks after the recovery.

Director General of the Institute, Innocent Ujah, gave the warning on Thursday at a one-day sensitisation programme on the EVD at the Lagos State University (LASU).

Ujah, whose presentation was titled, ‘Clinical features and management of Ebola virus Disease’, stressed that men who have recovered from the illness should abstain from carnal knowledgeual intercourse till about eighth to ninth week of total recovery.

“Men who have recovered from the disease can still transmit the virus through their semen for up to seven weeks after recovery from illness.

“Any man that has recovered from the Ebola disease should wait for eight to nine weeks after recovery before having carnal knowledgeual intercourse, in order not to transmit the virus to another person,” he counselled.

Ujah, a gynaecologist, said NIMR was aware that the virus is coming and it has started preparing for it, adding that the institute is preparing to upgrade its facilities to take care of the disease and other deadly ones.

He reiterated that there is no definite therapy or vaccine against Ebola, noting that Nigerians have never paid sufficient attention to infectious diseases like this.

Ujah added that this is the first time Nigerians have responded to emergency.

Also, Adeyeye Arigbabuwo, whose presentation was entitled, ‘EVD in the community: The myths and prevention’, stated that myths refer to a lot of rumours, beliefs, perception from ordinary taboos, culture-guided understanding, sentiments and at some extreme, hard views that may not have scientific backing but being peddled around to create scare or fear with or without deliberate intentions.

According to him, examples of myths around Ebola recently include the use of salt in water to bathe for reduction of Ebola virus chances of infectiousness, the chewing of bitter cola in large quantity to prevent contagiousness of Ebola virus and the consumption of some daily quantity of condensed milk to prevent Ebola virus attack among others.

He stated that in breaking these myths, “it is good to note that Ebola virus is the cause of Ebola virus disease”.

“It is when we come in contact with an infected living person or dead corpse and we have contacts with either their body fluids or secretions like blood, vomiting, stool, saliva, sweat etc that we are likely to be infected,” Arigbabuwo said

Do you have article or news for publication? Email it to You are not allowed to view links. Register or Login

Sources: Dailyindependent
Knowledge Is Power – Seek For It

Offline [Not Shown, Login to View]

  • Forum Guide
  • Level 4 (Dedicated)
  • ******
  • Posts: 1056
  • Respect: +267
  • Gender: Male
  • Location: Ibadan, Oyo State of Nigeria
  • 1st Chamber
  • My Rank: 86
Local vegetable ‘cure’ for Ebola validated
« Reply #9 on: Sep 11, 2014 »
0
Can drinking vegetable juice freshly made with jute (Corchorus olitorius, Ewedu in Yoruba, Rama in Hausa and Fulani) in an empty stomach prevent and cure the dreaded Ebola Virus Disease (EVD)

A PROFESSOR of medicine and consultant ophthalmologist at the College of Medicine University of Lagos (CMUL)/Lagos University Teaching Hospital (LUTH), Adebukola Adefule Ositelu, last week, in Lagos, recommended that drinking vegetable juice freshly made with jute (Corchorus olitorius, Ewedu in Yoruba, Rama in Hausa) in an empty stomach can prevent and cure the dreaded Ebola Virus Disease (EVD).

A consultant botanist at the University of Lagos, Prof. Toyin Ogundipe, told The Guardian that Corchorus olitorius belongs to the family of Tiliaceae. It is commonly called jute in English language, Moroheiya by the Japanese and Ewedu by the Yoruba tribe of Nigeria.

According to The Useful Plants of West Tropical Africa by H. M. Burkill, “in Nigerian cuisine, especially amongst the Yorubas, it is commonly used in a stew known as ewedu, a condiment to other starch-based foods such as amala. The Hausa people of Nigeria and their Fula neighbours call it rama. They use it to produce soup (taushe) or boil the leaves and mix it with kuli-kuli (groundnut cake) to form a dish known as kwado in Hausa. The Hausa peasant farmers cultivate it beside their corn-stalk constructed homesteads or among their main crops in their farms. The Hausa and Fulani peoples also use jute leaves to treat some diseases.”

Ogundipe said that previous studies had shown that jute is an excellent source of vitamin A and C, fiber, minerals including calcium and iron and other micronutrients.

The professor of botany said the plant has been reported to be demulcent, deobtruent (having power to clear or open the natural ducts of the fluids and secretions of the body), diuretic, lactagogue (encourages lactation that is flow of breast milk), purgative and tonic, as well as a folk remedy for aches and pains, dysentery, enteritis, fever, dysentery and tumors.

The methanolic extract of its seeds has been reported to show a broad spectrum of antibacterial activity. Its aqueous extract has been reported to possess opioid-mediated anti-nociceptive activity (reducing sensitivity to painful stimuli). The anticonvulsive property of its methanolic extract in mice has also been reported. Its leaf extract has been reported to reduce elevation of postprandial blood glucose levels in rats as well as humans.

Jute, other vegetables are very nutritious

The results of nutritional composition of Corchorus olitorius leaves, according to a study published recently in Animal Production Research Advances showed that the leaves contained 18.38±0.32 per cent ash, 12.54±0.10 per cent crude protein, 11.99±0.50 per cent crude lipid and 19.56±0.18 per cent available carbohydrate.
   
The researchers wrote: “The leaves also had high energy value of 200.78±3.54 kcal/100g respectively. Mineral analysis revealed that potassium (2814.15±8.08 mg/100g) and magnesium (76.69± 0.13 mg/100g) were the dominant elements. The leaves also contained appreciable concentrations of sodium/Na (54.56±0.42 mg/100g), calcium/Ca (30.55±0.05 mg/100g), phosphorus/P (6.68±0.02 mg/100g), copper/Cu (2.52±0.02 mg/100g), iron/Fe (19.53±0.09 mg/100g), manganese/Mn (5.95±0.04 mg/100g) and zinc/Zn (4.71+0.01 mg/100g).

“The present result confirmed that Corchorus olitorius leaves are rich sources of potassium, iron, copper, manganese and zinc as well as high energy values essential in human and animal nutrition.”

Also, researchers have found that jute (Corchorus olitorius) had highest ash, crude fibre, protein, lipid and carbohydrate content (0.83 per cent), (0.33 per cent), (6.21 per cent), (5.08 per cent) and (6.25 per cent) respectively than mint leaf (Ocimum gratissimum), waterleaf (Talinum triangulare) and fluted pumpkin leaf (Telfaria occidentalis).
       
The study titled “Nutritional evaluation of some staple leafy vegetables in Southern Nigeria” was published in International Journal of Agricultural and Food Science Universal Research Publications.
 
The researchers from the College of Health Sciences, Igbinedion University, Okada, Edo State, wrote: “Corchorus olitorius (jute) is a native plant of tropical Africa and Asia, and has since spread to Australia, South America and some parts of Europe. Its leafy vegetable is popularly used in soup preparation and folk medicine for the treatment of fever, chronic cystitis, cold and tumours. The young shoot tips can be eaten raw or cooked and it contains high levels of protein and vitamin C. Corchorus olitorius is usually recommended for pregnant women and nursing mother because it is believed to be rich in iron.

They added: “Four different green leafy vegetables commonly consumed in southern parts of Nigeria were analyzed with a view to determine the nutrient composition of these vegetables… The results revealed that Talinum triangulare had the highest amount of moisture (89.47 per cent) while Corchorus olitorius had highest ash, crude fibre, protein, lipid and carbohydrate content (0.83 per cent), (0.33 per cent), (6.21 per cent), (5.08 per cent) and (6.25 per cent) respectively. The vitamin analysis also revealed that Telfaria occidentalis contained the highest ascorbic acid, niacin and thiamin content (356.11 mg/100 g), (0.74 mg/100 g) and (0.08 mg/100 g) respectively. Talinum triangulare had the highest amount of riboflavin (0.18 mg/100 g). The results obtained in this work clearly indicate that the four leafy vegetables are cheap and readily available source of the nutrients analyzed.

 “…Scent leaf Ocimum gratissimum is commonly used in folk medicine to treat different diseases such as upper respiratory tract infection, diarrhoea, skin diseases, pneumonia and also cough and conjunctivitis. Ocimum gratissimum is grown for the essential oils in its leaves and stems. Eugenol, thymol, citral, geraniol and linlool have been extracted from the oil. Essential oils from the plant have been reported to possess an interesting spectrum of antifungal properties. The antinociceptive property of the essential oil of the plant has been reported.

“The whole plant and the essential oil are used in traditional medicine especially in Africa and India. The essential oil is also an important insect repellent. O. gratissimum is germicidal and has found wide use in toothpastes and mouth washes as well as topical ointments. It is used as an excellent gargle for sore throats and tonsillitis. It is also used as an expectorant and a cough suppressant. The plant extract is used against gastrointestinal helminths of animals and man. In addition, O. gratissimum carminative properties make it a good choice for upset stomach. It is used as an emetic and for hemorrhoids. The plant is also used for the treatment of rheumatism, paralysis, epilepsy, high fever, diarrhoea, sunstroke, influenza, gonorrhea and mental illness. In addition, the plant is used as a spice and condiment in the southern part of Nigeria.
 
“Water leaf (Talinum triangulare), a leafy vegetable is among the various classes of vegetables that are grown in many parts of Nigeria. Oyolu reported that the leaves of Telfaria occidentalis, together with the edible shoots contain moisture; crude protein, carbohydrates, oils, ash and iron, while Longe et al. reported that the minerals namely: calcium, potassium, magnesium, iron, sodium and phosphorus are concentrated in the testa, pulp and husk. Oboh has reported that dietary intake of the leaf could prevent garlic- induced haemolytic anaemia in rats. The aqueous extracts of Telfaria occidentalis had been reported to reduce blood glucose level and also have anti-diabetic effects in glucose induced hyperglycaemic streptozotocin (STZ) induced diabetic mice, while it did not alter the glucose levels in normoglyceamic mice. Recently, Dina et al. reported that the aqueous extract of Telfaria occidentalis leaf could assist in the purging of the gastrointestinal tract as revealed by the purgative effect of the aqueous extracts of Telfaria occidentalis leaf on isolated guinea pig ileum and he concluded that there are some pharmacological effects underlying their mode of action.”

The researchers further stated: “The substantial amount of fibre in all the vegetables shows that they can help in keeping the digestive system healthy and functioning properly. Fibre aids and speeds up the excretion of waste and toxins from the body, preventing them from sitting in the intestine or bowel for too long, which could cause a build-up and lead to several diseases. All the vegetables studied contain appreciable amount of protein, which indicates that the vegetables can be used for building and repairing of body tissues, regulation of body processes and formation of enzymes and hormones. Proteins also aid in the formation of antibodies that enable the body to fight infection. Proteins serve as a major energy supplier.

“These vegetables are good sources of lipids. Lipids are essential fats that play a very important role in the human body. Lipids help with brain function, joint mobilization and even energy production. They also help the body to absorb fat-soluble vitamins such as vitamins A and E. The percentage of carbohydrate in all the vegetable studied is an indication that the leafy vegetables can be used to regulate various metabolic processes in the body as key molecules in the central metabolic pathways of the body. Carbohydrate also serves as stored forms of energy as glycogen in liver and muscles. It also provides major source of energy and responsible for breaking-down of fatty acids and preventing ketosis.

These vegetables are also good sources of ascorbic acids, niacin, riboflavin and thiamin. Natural ascorbic acid is vital for the body performance. Lack of ascorbic acid impairs the normal formation of intercellular substances throughout the body, including collagen, bone matrix and tooth dentine. A striking pathological resulting from this defect is the weakening of the endothelial wall of the capillaries due to a reduction in the amount of intercellular substances. Therefore, the clinical manifestations of scurvy hemorrhage from mucous membrane of the mouth and gastrointestinal tract, anemia, pains in the joints can be related to the association of ascorbic acid and normal connective tissue metabolism. This function of ascorbic acid also accounts for the requirement for normal wound healing.

“As a result of the availability of ascorbic acid in all the vegetables, they can be used in herbal medicine for the treatment of common cold and other diseases like prostrate cancer.

“In conclusion the study has showed that the leafy vegetables contain appreciable level of nutrients, which are readily available. Hence they could be consumed to supplement the scarce or non-available sources of nutrients.”

Jute boosts blood parameters

 Nigerian researchers have found that that aqueous extract of Corchorus olitorius could have both harmful and beneficial potentialities on the blood chemistry of male albino rats.
 
The study was published last year in IOSR Journal of Dental and Medical Sciences.

The study titled “Effect of Corchorus olitorius Extract On Haematological and Plasma Biochemical Parameters in Male Albino Rats” was published by K. O. Oyedeji And A. F. Bolarinwa from the Department of Physiology, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State; and Department of Physiology, College of Medicine, University of Ibadan, Oyo State.

The researchers investigated the effect of oral administration of aqueous extract of Corchorus olitorius (AECO) at doses of 250 mg/kg BW, 500 mg/kg BW and 750 mg/kg BW on haematological and plasma biochemical parameters in male albino rats. The extract was administered on daily basis for 30 days and blood samples were collected for haematological and plasma biochemical assays.

Treatment of rats for 30 days with all the treatment doses (250 mg/kg body weight/BW, 500 mg/kg BW, 750 mg/kg BW) of AECO caused insignificant (p>0.05) changes in Packed Cell Volume (PCV), Red Blood Cell (RBC), Mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC), platelet, neutrophil, lymphocyte, eosinophil and monocyte values relative to their respective controls, but caused significant decrease in Total White Blood Cell (TWBC) count relative to the control.

Treatment of rats with 750 mg/kg BW of AECO cause significant increase in total protein level relative to the control, but 250 mg/kg BW and 500 mg/kg BW of AECO caused significant reductions in globulin levels.

The study reads: “Traditionally, its leaves are used in the treatment of pain, fever, chronic cystitis and tumors.

“Its seeds have been reported to posses estrogenic activity as well as contain high content of hydrogen cyanide and several cardiac glycosides. Its extract has been reported to suppress transformation of the aryl hydrocarbon receptor induced by dioxins. Its polyphenolic isolate has been reported to have anti-obesity effect. Its aqueous extract has also been reported to have protective effect in arsenic-induced myocardial injury.”

The researchers further explained: “The LD50 gives a measure of the immediate or acute toxicity of a test substance. This study revealed that AECO at high doses of 2500 mg/kg BW, 500 mg/kg BW and 7500 mg/kg BW had no apparent toxic and lethal effects on the animals which probably indicates that the extract has high safety index. This could be due to hepatic metabolism of the toxic potentialities of the extract, since the extract is administered orally.

“The values obtained for RBC showed the non-significant effects of 30-day treatment of rats with AECO on red blood cells (RBC) counts and indices relating to it (PCV, MCV, MCH and MCHC) when compared with the control. This is an indication that there was no destruction of red blood cells and no change in the rate of production of RBC (erythropoiesis). This also shows that AECO does not have the potential to stimulate erythropoietin release from the kidneys, which is the humoral regulator of RBC production.

“The non-significant effects of the treatment of rats with AECO at all doses also indicate that there were no change in the oxygen-carrying capacity of the blood and the amount of oxygen delivered to the tissues since RBC is very important in transferring respiratory gases. It has been reported that values of RBC and associated parameters lower than normal ranges are indicative of anemic conditions while higher values are suggestive of polycythemia, thus, the treatment of rats with AECO may not have the potential to induce anemia or polycythemia.
 
“Also, the treatment of rats with AECO at all treatment doses may not have adverse effects on the bone marrow, kidney and haemoglobin metabolism, since it has been reported that only substances which significantly affect the values of red blood cells and associated parameters would have effects on the bone marrow, kidney and haemoglobin metabolism.
       “The significant reduction in TWBC count caused by AECO suggests that the immune system has been compromised. Contrary report was given by Adewusi and Afolayan in Pelargonium reniforme extract treated rats. The extract caused non – significant changes in the MCV and MCH values which could be an indication of absence of macrocytic anaemia since increased MCV an MCH values are known to be indicative of macrocytic anaemia. Also, AECO caused non- significant change in the MCHC value which suggest and absence of hereditary spherocytosis since MCHC values are known to be elevated in hereditary spherocytosis.

“The insignificant change in neutrophil count caused by extract probably indicates that the ability of the body to attack and destroy invading bacteria, viruses and other injurious agents (Phagocytosis) has not been compromised. The non-significant change in lymphocyte count suggests that the acquired immune responses of the body has not been compromised by the extract; while the significant increase in monocyte count probably indicates that the phagocytic function of the body has been enhanced by the extract. The non–significant change in eosinophil count probably indicates that the anti-allergic and anti-parasitic infectious response of the body have not been compromised by extract.

“Also, the insignificant change in the platelet count caused by extract could be an indication that it does not has the potential to stimulate thrombopoietin production with the hemostatic capability of the blood maintaining the status quo since platelets mediate in the blood –clotting mechanism.

“AECO at high doses caused significant increase in total protein levels, which probably indicates that the buffering capacity of the blood and body fluid balance have been enhanced. Similar report was given by Adewusi and Afolayan in Pelargonium reniforme extract treated rats. At lower doses the extract caused significant reductions in globulin levels, which could indicate a compromise in both the natural and acquired immunity of the body against invading organisms. The extract caused insignificant change in albumin level, which suggests the maintenance of status quo in plasma level of metals, ions, fatty acids, amino acids, bilirubin and enzymes.

“Contrary report was given by Adedapo et. al. in rats treated with P. amarus and C. anontifolius extracts. The extract caused insignificant change in the activity of alanine transaminase (ALT), which probably indicates that the hepato-protective potential of the extract has not been compromised. The extract also caused non- significant change in the activity of aspartate transaminase (AST), which could indicate absence of tissue necrosis induction by the extract.


The study titled, “Anti diabetic Activity Of Ethanolic Seed Extract Of Corchorus olitorius” was published by Maxwell Osaronowen Egua, Emmanuel Udo Etuk, Shaibu Oricha Belloc, and Sanusi Wara Hassand from Usmanu Danfodio University, Sokoto State.

The researchers wrote: “The ethanolic seed extract of Corchorus olitorius was studied to ascertain its possible antidiabetic effect. Corchorus olitorius seeds were pulverized to powder and Soxhlet extractor was used for extraction of the seed compound with ethanol. The study was carried out using normoglycaemic, glucose challenged and alloxan induced diabetic albino rats. The dose range tested for the extract was between 100- 1000mg/kg body weight of the rats. The effects were compared with a glibenclamide (0.2mg/kg) treatment and a normal saline treatment control groups. A repeat dose study was carried out for 14 days at a fixed dose of 500mg/kg and the glycosylated haemoglobin and insulin level determined. 
     
“The ethanolic seed extract of Corchorus olitorius was found to contain alkaloids, tannins, flavanoids, glycocides, saponin, cardiac glycocides, anthraquinons, steroids and volatile oil. The extract significantly (p≤0.01) reduced blood sugar levels in normoglycaemic, OGTT and diabetic rats. This was further supported by reduction in the glycosylated haemoglobin and increase in the insulin level determined.

 In  “Conclusion, the results of this study showed that the ethanolic seed extract of C.O has great potentials as an anti diabetic remedy due to the ability of the extract to lower blood glucose levels in normal rats, diabetic rats and also suppress postprandial rise in blood glucose levels.”

Source:  You are not allowed to view links. Register or Login
Knowledge Is Power – Seek For It

Offline [Not Shown, Login to View]

  • Administrator
  • Level: Mentor
  • ******
  • Posts: 259676
  • Respect: +7996
  • Gender: Male
  • Location: Benin City
  • 18th Chamber
  • My Rank: 85
Hmmm, some interesting info here Aare. Thanks for sharing
Leave it for God, don't worry yourself. Leave it for God, don't cry no more.

Offline [Not Shown, Login to View]

  • Forum Guide
  • Level 4 (Dedicated)
  • ******
  • Posts: 1056
  • Respect: +267
  • Gender: Male
  • Location: Ibadan, Oyo State of Nigeria
  • 1st Chamber
  • My Rank: 86
You are not allowed to view links. Register or Login
Hmmm, some interesting info here Aare. Thanks for sharing

You are welcome our indefatigable Boss Tony....
Knowledge Is Power – Seek For It

 

Related Topics

  Subject / Started by Replies Last post
2 Replies
512 Views
Last post May 09, 2014
by [Not Shown, Login to View]
1 Replies
375 Views
Last post May 09, 2014
by [Not Shown, Login to View]
1 Replies
481 Views
Last post Jul 09, 2014
by [Not Shown, Login to View]
4 Replies
519 Views
Last post Jul 18, 2014
by [Not Shown, Login to View]
2 Replies
415 Views
Last post Jul 26, 2014
by [Not Shown, Login to View]

TinyPortal © 2005-2011
SimplePortal 2.3.5 © 2008-2012, SimplePortal